Tag: androgens

During the last 22 years we observed 1790 patients with incidentally found adrenal tumours, so-called adrenal incidentalomas (AI). Our first publication on AI, in 1992, was based on an analysis of 64 patients observed at our department [1]. Since that time our group of patients with AI has grown and is worthy of evaluation...

Aromatase is a member of the cytochrome P450 superfamily, a very large family of enzymes catalyzing incorporation of an atom of oxygen into an organic molecule, called hydroxylases. These widespread membranebound proteins are present in most animal, plant, and human tissues, such as the liver, and they are essential for the synthesis of cholesterol and steroid hormones and metabolism of xenobiotics and fatty acids...

Hypogonadism is probably very common among patients with advanced disease. It may result from the disease itself but might also be caused or exacerbated by the drugs used to treat these patients and their symptoms. Opioids are notorious for their ability to depress the production of androgens by both adrenals and gonads...

Stress is generally a natural phenomenon that affects behaviour, physiological processes, and neuroendocrine, neurochemical, neurological and immune responses. Many somatic and mental disorders are thought to result from chronic stress.

Breath-hold diving has a very long tradition in certain parts of the world [1]. As a specific sport, it attracts the attention of scientists as well as athletes [2, 3].Breath-hold divers are regularly exposed to extreme physiological and psychological distress. It has been reported that 10% of static apnoea competitors are disqualified from international events after encountering acute medical complications (e.g. complete loss of consciousness) [4].