Tag: autophagosome
Lista treści zawierających tag autophagosome:
The autophagic process was first described by Clark in 1957 using electron microscopy, but the term “autophagy” was introduced for the first time in 1963 by Christian de Duve, who was awarded the Nobel Prize for his work on lysosomes. Autophagy (auto — self, phagy — eating) is defined as an evolutionarily conserved and strictly regulated lysosomal pathway that degrades cytoplasmic material and organelles and even microbial invaders [22, 36, 37, 39]. The other major degrading system, which is present only in mammals, is the ubiquitin-proteasome system (UPS) [44]. The UPS degrades soluble short-lived proteins, which must be tagged by ubiquitin to be recognised by the proteasome...
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Opublikowano: 2013-10-31 13:28:10
Oryginalne wydanie: 2013-06-05
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