Tag: immunohistochemia

Plurihormonality of pituitary adenomas can be defined as the ability of an adenoma to express more than one pituitary hormone. According to the recommendations of the WHO, the gonadotropinomas expressing both gonadotropins, i.e. FSH and LH, are not considered plurihormonal. The same concerns adenomas in patients with acromegaly, secreting prolactin in addition to GH [1]. Plurihormonal adenomas leading to the elevated concentrations of more than one pituitary hormone in blood are considered relatively rare...

The highly variable expression of SSTR subtypes in pituitary adenomas (PA) may partially explain why the subgroup ofsomatotropinomas or other adenomas do not respond to the therapeutic action of currently used long-acting somatostatin analogues like  octreotide or lanreotide....

Rak płuca to najczęściej występujący na świecie nowotwór złośliwy. Rokowanie w raku płuca pozostaje niekorzystne. Zgodnie z danymi epidemiologicznymi 5-letnie przeżycie uzyskuje się zaledwie u 10–15% pacjentów [1]...

Evidence collected over the years has demonstrated that cryptorchidism is associated with a defect in spermatogenesis and,  as a consequence, with either reduced fertility or infertility. However, the effect of cryptorchidism on Leydig cell function is less clear...

Recently, dopamine D2 receptors (RD2) have been found to be expressed in neuroendocrine tumours (NET), the tumourswhich arise from the diffuse neuroendocrine cells. Moreover, successful trials of the treatment of NET with cabergoline — D2 agonist,have been reported. These findings increase the interest of investigating RD2 expression in NET....