Tag: sudden death

The role of the central nervous system in the modulation and precipitation of sudden cardiac death has been a matter of controversy for decades. Establishing a cause-effect relationship in the setting of a cerebro-vascular event has been complex, as patients with stroke usually have risk factors for coronary artery disease as well...

Sudden unexpected death in epilepsy (SUDEP) is defined as sudden, unexpected, witnessed or unwitnessed, non-traumatic and non-drowning deaths in patients with epilepsy, with or without evidence of a seizure and excluding documented status epilepticus, in which a post-mortem examination does not reveal a toxicological or anatomical cause of death [1]. The incidence of SUDEP has been estimated from 0.5–1.4/1,000 person-years in people with treated epilepsy, and 9/1,000 person-years in candidates for epilepsy surgery [2]...

This is a 12-lead electrocardiogram (ECG) of a 26 year-old male patient with myotonic dystrophy type 1 (DM1) diagnosed eight years previously, with severe distal muscular weakness, gait, speech and mastication disorders, and mild mental retardation. A positive family history with similar manifestations was present (mother and brother, the latter presenting with sudden death at the age of 34)...

Randomized clinical trials (RCTs) have demonstrated the efficacy of implantable cardioverter-defibrillators (ICDs) in reducing sudden cardiac death (SCD) in specific patient populations. However, patients ≥ 65 years were under-represented in these trials and the overall benefit of ICDs may be diminished in older patients due to competing risks for death. We evaluate the published data on ICD efficacy at reducing all-cause mortality in patients ≥ 65 years and in patients ≥ 75 years...

Randomized clinical trials (RCTs) have demonstrated the efficacy of implan-table cardioverter- defibrillators (ICDs) in reducing sudden cardiac death (SCD) in specific patient populations.

A 34-year-old male with dilated cardiomyopathy and advanced heart failure was referred for defibrillator implantation for primary prevention of sudden cardiac death.