The presence of HER2 exon 20 insertion in patients with central nervous system metastases from non-small lung cancer — a potential application in classification for therapy
HER2 (ErbB2/neu) is a member of the ErbB family of four structurally related receptors of tyrosine kinase activity.Overexpression of ErbB-1 (EGFR) and HER2 is found in many human cancers, but the presence of these genes mutations determinesthe effectiveness of EGFR and HER2 tyrosine kinase inhibitors in the therapy of non-small cell lung cancer (NSCLC).
Język: polski
Profil:
pneumonologia
Rodzaj: Artykuł, Dostęp: Dla wszystkich, Odpłatność: Darmowe