Identification and analysis of mutations in the katG gene in multidrug-resistant Mycobacterium tuberculosis clinical isolates
A major role in the development of resistance of Mycobacterium tuberculosis to isoniazid (INH) is attributed tomutations in the katG gene coding for the catalase/peroxidase, an enzyme required for obtaining a pharmacologically active formof the drug. Analysis of mutations in the katG gene in M. tuberculosis strains may contribute to the development of reliable andrapid tests for detection of INH resistance.
Język: polski
Profil:
pneumonologia
Rodzaj: Artykuł, Dostęp: Dla wszystkich, Odpłatność: Darmowe