Predictors of mortality in patients with prosthetic valve infective endocarditis: A nation-wide multicenter study

Autorzy: Mehmet Ali Elbey¹, Mehmet Emin Kalkan², Serkan Akdag³, Kerem Ozbek⁴, Nihan Kahya Eren⁵, Sinan Demirtas⁶, Mehmet Ata Akil¹, Selim Topcu⁷, Mustafa Oylumlu¹, Zihni Bilik¹, Murat Yuksel¹ 1 - Dicle University School of Medicine, Depar tment of Cardiology. Diyarbakir, Turkey
2 - Kartal Kosuyolu Education and R esearch Hospital, Clinical Cardiology, Istanbul, Turkey
3 - Yuzuncu Yil University School of Medicine, Depar tment of Cardiology, Van, Turkey
4 - Gaziosman Pasa University School of Medicine, Depar tment of Cardiology, Tokat, Turkey
5 - Izmir Ataturk Education and R esearch Hospital, Clinical Cardiology, Izmir, Turkey
6 - Dicle University School of Medicine, Depar tment Cardiovascular Surgery, Diyarbakir, Turkey
7 - Ataturk University School of Medicine, Depar tment of Cardiology, Erzurum, Turkey

Artykuł: Pobierz w formacie PDF

Abstrakt

Background: Our aim was to investigate the clinical and prognostic features of the patients with prosthetic valve endocarditis (PVE) in a multicenter nation-wide study.

Methods: The present nation-wide study consisted of 75 consecutive patients with PVE treated at 13 major hospitals in Turkey from 2005 to 2012.

Results: The patients who died during follow-up were significantly older than the survivors and had higher C-reactive protein (CRP), creatinine, poor NYHA functional class and large vegetations. High creatinine level (odds ratio [OR] 2.6, 95% confidence interval [CI] 1.14–6.13), poor functional status (OR 24.5; 95% CI 3.1–196.5) and high CRP (OR 1.02; 95% CI 1.00–1.03) measured on admission were independent risk associates for in-hospital mortality.

Conclusions: High creatinine level, poor functional status and high CRP measured on admissionwere independent risk associates for in-hospital mortality, whereas a NYHA class of III/IV and high CRP reflected independent risk for stroke/mortality end point.

Wydane przez: Via Medica
Data wydania: 2013-06-10
Język: angielski
Profil: choroby sercowo-naczyniowe

Tagi: prognostic factors, mortality, infective endocarditis,

Rodzaj: Artykuł, Dostęp: Dla wszystkich, Odpłatność: Darmowe