Cardiology Journal 2009, tom 16, nr 6
In this issue of ”Cardiology Journal”, Kosior et al. [1] report a randomized trial of propafenone versus quinidine for recent onset atrial fibrillation. They found that patients assigned to propafenone, as opposed to quinidine, had a greater chance of convertingto sinus rhythm earlier after drug administration. Specifically, propafenone 600 mg orally was compared to quinidine 400 mg initially then 200 mg every two hours in combination with intravenous digoxin to prevent a rapid ventricular response due to the anticholinergic effect of quinidine. Major adverse events were not observed, and minor events, although relatively common, were not statistically significantly different in the two arms.
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Opublikowano: 2010-10-11 12:50:49
Oryginalne wydanie: 2009-11-19
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