Endokrynologia Polska 2010, tom 61, nr 2

The Original papers section starts with reports on obesity, an important civilisation problem of the 21st century. The first report, authored by researchers from Gdansk, addresses the relationship between the amount of the adipose tissue and metabolic complications, adipokine levels and proinflammatory cytokine levels, and the effects of low-calorie diet on reducing chronic inflammation in overweight or obese patients...

IV Ogólnopolska Konferencja Naukowa „Postępy w diagnostyce i leczeniu guzów neuroendokrynnych”

There is a great deal of concern about the continuously increasing prevalence of vitamin D insufficiency in different age groups in the Polish population [1–3]. Vitamin D deficiency may cause not only rickets, osteomalacia, and osteoporosis but also may increase risk of many others diseases, e.g. diabetes, cancers (breast, colon, prostate), autoimmunological disease (multiple sclerosis, rheumatoid arthritis, lupus), cardiovascular diseases, and metabolic syndrome [3]...

Ophthalmopathy is a common manifestation of Graves’ disease. The association between “poppy eyes” and goitre was described as early as AD 1000 by the Persian physician and philosopher Avicenna [1]. Ophthalmopathy is most commonly seen in patients with Graves’ hyperthyroidism where it is called “Graves’ ophthalmopathy” [2, 3]...

One of the causes of premature ovarian failure (POF) is related to chromosomal abnormalities. Portnoi et al. [1] performed cytogenetic examinations in 90 patients with diagnosed POF and found an abnormal karyotype in 8.8% of cases. The group also included one case of 47,XXX. Other literature data confirm that the 47,XXX karyotype may be associated with POF revealing itself in during puberty as well as the reproductive period...

Multiple endocrine neoplasia type 1 (MEN 1) is a rare autosomal dominant inherited endocrine disorder characterized by pancreatic, parathyroid, and anterior pituitary tumours. Hypercalcaemia due to parathyroid tumours is usually the first manifestation of MEN 1 and occurs in 90% of patients...

Polycystic ovary syndrome (PCOS) is one of the most common reproductive disorders and affects between 5-10% of premenopausal women [1]. It is characterized by chronic anovulation, clinical and/or biochemical hyperandrogenism, and polycystic ovary morphology...

The human body is endowed with a complex physiological system that maintains relatively constant body weight and fat stores despite the wide variations in daily energy intake and energy expenditure. With weight loss, compensatory physiological adaptations result in increased hunger and decreased energy expenditure, while opposite responses are triggered when body weight increases...

Epidemiological data show that thyroid disorders such as goiter, nodularity, and hyperthyroidism are more common in areas of long-standing iodine deficiency. After iodine supplementation, it is supposed that some of these thyroid disorders should be decreased [1–7]. Ultrasonography is useful for several aspects of thyroid gland investigation, including measurement of size,and finding nodularity and echogenicity [8, 9]...

We investigated the effects of insulin on glucose transport in human peripheral lymphocytes using flow cytometry. We hypothesized that lymphocytes could be used as tools to study insulin action at the cellular level and facilitate the investigation of mechanisms that lead to insulin resistance...