Acta Angiologica 2008, tom 14, nr 4

Lower limb varices have been known and described for more than 3500 years. Through the ages, numerous modalities have been used in the management of this condition. Many of these methods evolved and, after some modifications, remain in use. Surgical techniques of major importance in the management of varices of the greater saphenous vein include crosscutting of the venous ostium (crossectomy) and partial or complete removal of the venous trunk (stripping)...

The pathogenesis of abdominal aortic aneurysms (AAA) and aorto-iliac occlusive disease (AIOD) is multifactorial, and both genetic and environmental factors are involved in the initiation and progression of pathological changes in the aorta. This study is concerned with associations between the age of AAA and AIOD surgical repair and the classical vascular risk factors as well as the paraoxonase 1 (PON1)–108C>T genotypes...

Acute in-stent thrombosis can occur in patients with peripheral arterial disease previously treated with endovascular interventions with stent implantation. Local fibrinolysis is an alternative treatment to endarterectomy. This study aims to determine the outcomes of local fibrinolysis in patients with arterial instent thrombosis..

Currently gene therapy is mostly focused on cancer treatment trials, cardiovascular and infectious diseases. Nowadays gene therapy for cardiovascular diseases is recognised thanks to successful clinical trials that have used mainly genes encoding proangiogenic citokines,eg vascular endothelial growth factor (VEGF), fibroblast growth factor (FGF), hepatic growth factor (HGF)...

Due to the common use of oral anticoagulants in the treatment of vascular diseases and their complications the number of patients treated chronically with anticoagulants who require diagnostic and therapeutic procedures is still growing up. This concerns often the patients scheduled for surgical procedures that, in the cases of anticoagulant therapy continuation, can lead to the high rate of bleeding...