Diabetologia Doświadczalna i Kliniczna 2008, tom 8 nr 4

The prevalence of type 1 and type 2 diabetes mellitus is gradually growing. It has also been demonstrated that the age at diagnosis is decreasing. Diabetes mellitus is currently an enormous individual and social problem...

Diabetes mellitus is a pandemic of the beginning of the 21st century claiming an increasing number of lives each year. It is estimated that approximately 2 million people in Poland are affected by the condition, half of whom are unaware of its presence...

Diabetes is a chronic progressive disease of an epidemic character, causing considerable human, as well as social and economic losses. It concerns people of all ages and in all countries [1–3]. Permanent health deterioration related to the disease often results in restricting patients’ daily tasks, and in extreme cases it makes their performance impossible [3, 4]...

Diabetes mellitus (DM) is one of the most common chronic diseases in children. The prevalence of type 1 DM in many regions of the world is increasing annually by 2.5–3.0% and the disease is affecting younger and younger age groups [1, 2]. Primary school children spend several hours at school each day, where they must take their insulin injections and are running the risk of complications, such as hypoglycaemia...

Glucose is transported from the blood into the cells by transmembrane transporting proteins encoded by two separate gene families. The first family is represented by the so-called glucose co-transporters (SGLT, sodium/glucose co-transporters). These proteins transport glucose into the cells by means of active transport, against the concentration gradient...

While the tendency in the treatment of diabetes mellitus to achieve glucose values as close as possible to values observed in healthy individuals reduces the likelihood of microvascular complications, neuropathy and macrovascular complications, it simultaneously increases the risk of hypoglycaemia. In the Diabetes Control and Complications Trial (DCCT) evaluating patients with type 1 diabetes mellitus, severe hypoglycaemia requiring intervention of other people occurred in 10% of the patients managed conventionally (two insulin injections daily) and 26% of patients receiving intensive insulin therapy with the respective percentages for hypoglycaemic coma equalling 6% and 20%...

Cukrzyca stanowi poważny problem społeczny i medyczny [1]. Ciągle wzrasta liczba chorych i zwiększa się grupa pacjentów, u których występują późne powikłania [2]. Problem ten jest szczególnie widoczny w przypadku cukrzycy typu 2, stanowiącej ponad 80% wszystkich przypadków tej choroby...

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