Endokrynologia Polska 2011, tom 62, nr 6

Przed Wami już ostatni w tym roku numer naszego czasopisma. Dedykujemy go obchodzącej 10-lecie swojego powstania Katedrze i Klinice Endokrynologii, Zaburzeń Metabolicznych i Chorób Wewnętrznych Pomorskiego Uniwersytetu Medycznego w Szczecinie. Koleżanki i Koledzy z zespołu Profesora Anhellego Syrenicza, we współpracy z innymi Katedrami, przedstawiają w nim swoje osiągnięcia w pracy naukowo-badawczej...

Spotykamy się często na zjazdach i konferencjach endokrynologicznych. Czasami występuję na nich jako wykładowca, czasami jestem tylko słuchaczem, a niekiedy mam przyjemność wystąpić w charakterze osoby pobudzającej dyskusję i wymianę poglądów. Część z Państwa znam osobiście i łączy nas przyjaźń, niektórzy z Was są „znajomymi twarzami”, które chciałbym bliżej poznać...

We investigated whether the vitamin D3 receptor gene (VDR) polymorphism can modulate therapeutic response of functional hypothalamic amenorrhea (FHA) patients to the oestroprogestagen (EP) treatment...

Obesity has been associated with low-grade systemic inflammation, potentially leading to insulin resistance, type 2 diabetes, dyslipidemia, and cardiovascular diseases. Even moderate weight loss through dietary changes and physical exercise is effective in preventing and managing obesity-associated disorders...

There is increasing evidence that vitamin D deficiency is common and has been associated with several non-bone related outcomes, including insulin resistance, type 2 diabetes and cardiovascular disease. The influences of gender, puberty, and adiposity on serum hydroxyvitamin D (25-OH-D) levels and the relationship between 25-OH-D and insulin resistance in obese children were studied...

The purpose of this study was a retrospective analysis of outcomes following laparoscopic adrenalectomy (LA) performed for benign adrenal tumours responsible for various endocrinological disorders. The patients were diagnosed with non-functioning (NFT) and functioning adrenal tumours (FT) including pheochromocytoma (PH), Conn’s syndrome (CO) and Cushing’s (CS) syndrome...

Different forms of interferon alpha (IFN-α) have been used for several years in the treatment of chronic viral hepatitis type C (CVHC). Currently, pegylated forms of interferon alpha (PegIFN-α) in combination with ribavirin is the standard treatment. During therapy with IFN-α, side-effects occur, including thyroid diseases...

Several studies have assessed natriuretic peptides in patients with thyroid disorders, and these studies have provided contrasting results. This difference may be partially explained by the presence of concomitant disorders of the cardiovascular system in participants...

Prolactin (PRL) exists in human blood in several molecular forms. Macroprolactin (MaPRL), which most often consists of monomeric PRL and immunoglobulin G, has the highest molecular weight but no biological activity. Immunoassays do not distinguish MaPRL from monomeric PRL, what can lead to an incorrect diagnosis of hyperprolactinaemia. The most commonly used technique to separate the isoforms of PRL is precipitation with polyethylene glycol (PEG)...

Puberty is a critical bone mineralisation period, and peak bone mass attained by adolescent girls is one of the most significant predictive factors for postmenopausal osteoporosis. Adolescent girls’ peak bone mass depends on genetic factors as well as on general condition, nutritional status and body mass; lifestyle is also important, along with physical exercise and the use of prescription drugs...