Tag: coronary artery disease

Common variants of the renin–angiotensin system (RAS) genes have been linked to a higher risk of coronary  artery disease (CAD) and its complications.  To determine the prognostic significance of a combination of three common polymorphisms of RAS genes (angiotensin  converting enzyme — ACE Ins/Del, angiotensin receptor type 1 — AGT1R A1166C and angiotensinogen — ATG M235T) in  patients with CAD...

Despite significant advances in revascularization techniques and medical therapy, there remains a significant population of patients who continue to have intractable angina symptoms. This review aims to define the patients with refractory angina pectoris (RAP) and to present the therapeutic options currently available for this condition...

Coronary artery disease (CAD) and cancer remain the leading causes of death in most developed countries. Elucidating the genetic components that contribute to their pathogenesis is challenging. In this case-control association study, we examine the association of single nucleotide polymorphisms (SNPs) in paraoxonase 573 A/G genes, methylene tetrahydrofolate reductase (MTHFR) 677 C/T and angiotensin-converting enzyme (ACE) gene insertion/deletion (I/D) polymorphism with CAD independently, as well as synergistically, in a north Indian population...

Although plasma pigment epithelium-derived factor (PEDF) levels have been shown to be significantly correlated with the levels of creatinine (Cr) in type 2 diabetes, little is known about the association between PEDF levels and renal dysfunction in patients with coronary artery disease (CAD)...

Kalcyfikacja naczyniowa (VC), a zwłaszcza kalcyfi- kacja naczyń wieńcowych, stanowi ważny problem kliniczny chorych dializowanych. Uważa się, że VC odpowiada za znaczną część zwiększonej śmiertel- ności obserwowanej w tej populacji chorych. Do rozwoju VC dochodzi we wczesnych okresach prze- wlekłej choroby nerek. Patogeneza VC jest złożona i nie do końca poznana...

We hypothesised that melatonin may represent a safe somniferous drug for cardiac patients, and assessed the effects of administering 5 mg of melatonin daily before bedtime for 30 days in patients with coronary artery disease (CAD) regarding changes in the nocturnal breathing pattern...

Fragmentation of QRS (fQRS) complex is an easily evaluated non-invasive electrocardiographic parameter. Fragmentation of narrow QRS is defined as presence of an additional R wave (R′) or notching in the nadir of the S wave, or the presence of > 1 R′ in 2 contiguous leads, corresponding to a major coronary artery territory on the resting 12-lead ECG. Fragmentation of wide complex QRS consists of various RSR patterns, with more than 2 R waves (R′′) or more than 2 notches in the R wave, or more than 2 notches in the downstroke or upstroke of the S wave.

Normal exercise SPECT studies are associatedwith a low event rate. The association of the negative SPECTand positive coronary angiography with the results for the longtime follow up was determined.

Negative emotional conditions contribute to the development of coronary artery disease (CAD). Depression and anxiety are prognostic factors in patients with CAD. The aim of our study was to investigate the association between emotional conditions and left ventricular (LV) systolic functions in CAD. 

Background: QRS complex fragmentations can frequently be seen on routine ECG with narrow or wide QRS complex. Fragmented QRS complexes (fQRS) are defined as various RSR' patterns (≥ 1 R' or notching of S wave or R wave) in two contiguous leads corresponding to a major coronary artery territory. In previous studies, fQRS has been associated with increased morbidity and mortality, sudden cardiac death and recurrent cardiovascular events. The causative relationship between fQRS and cardiac fibrosis has been shown, but it has not been extensively studied whether there are different mechanisms for the development of fQRS...