Tag: coronary artery disease

The aim of this study was to test whether there was an association between systemic levels of insulin like growth factor-1 (IGF-1), IGF-1 binding protein-3 (IGFBP3) and selected parameters of lipid metabolism depending on the lipid-lowering therapy. This work was conducted in patients described by us previously who had either highly probable, or documented, coronary artery disease, and controlled serum lipids with prolonged statin therapy.

Type 2 diabetes (T2DM) patients are at increased risk of cardiovascular events despite long-term acetylsalicylic acid (ASA) therapy. This study was performed to establish the prevalence of high platelet reactivity (HPR) on ASA in T2DM and to identify its predictors.

Elevated values of heart rate (HR) and insulin resistance (IR) reflect enhanced sympathetic nervous system activity and may be connected to the development of coronary artery disease (CAD) and diabetes.

The receptor activator of nuclear factor-Kb ligand (RANKL) is recently known as an important factor in osteoclastogenesis. Osteoprotegerin (OPG), a member of the tumor necrotic factor receptor family and a decoy receptor for RANKL plays its role in bone remodeling by blocking RANKL-ligand [1]. Actually it is the indirect inhibitor of the osteoclasts...

Sponsored by the National Heart, Lung, and Blood Institute, the Future Revascularization Evaluation in Patients with Diabetes Mellitus: Optimal Management of Multivessel Disease (FREEDOM) trial enrolled patients with diabetes mellitus (DM) and multivessel coronary artery disease (CAD) in a treatment with a coronary artery bypass grafting (CABG) surgery or a percutaneous coronary intervention (PCI) with sirolimus-eluting stents (SES) and paclitaxel-eluting stents (PES)...

Various mechanisms involved in the formation of thrombosis and regulation of coagulation have been identified to stabilize coronary atheromatous plaques. Recent research has supported the central role of coagulative factors in advancing atherosclerosis and causing coronary artery disease (CAD) [1–3]. In this regard, coagulation factor VII seems to have an essential role in the initiation and extension of coronary atherosclerosis [4, 5]...

Zakład Radiologii Uniwersyteckiego Centrum Klinicznego w Gdańsku dysponuje nowoczesnym dwuźródłowym 128-warstwowym tomografem komputerowym. Zastosowanie dwóch układów lampa-detektor do pełnej rekonstrukcji pojedynczego obrazu wymaga jedynie jednej czwartej obrotu gantry, co pozwala na dwukrotną poprawę rozdzielczości czasowej w porównaniu do skanerów jednoźródłowych. Ma to istotne znaczenie w obrazowaniu serca, które jest narządem o dużej przestrzennej ruchomości...